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Gallstone

life science Maturity 11-13

Small stones can grow inside you.

Human gallstones 2015 G1.jpg
Human gallstones 2015 G1.jpg
They live in a tiny part of your belly. Most of the time, you will not feel them. Some stones can cause a big tummy ache.
Gallstones.png
Gallstones.png
Do you want to stay healthy?

43 words

Small stones can grow inside you.

Human gallstones 2015 G1.jpg
Human gallstones 2015 G1.jpg
They live in a tiny part of your belly. Most of the time, you will not feel them.

Sometimes, a stone can block a path. This can cause a big tummy ache. The pain is in your upper belly.

Gallstones.png
Gallstones.png
It can even hurt your shoulder.

Some stones are made of fat. Other stones are made of different things. These stones can come in many colors. They can be yellow or green or brown.

Doctors use a special tool to see them. This tool uses sound to make a picture. This helps them find the stones.

If the stones hurt, a doctor can help. Some people need a small surgery. This can take the stones away.

126 words

Gallstones are small, hard objects. They form inside the gallbladder.

Human gallstones 2015 G1.jpg
Human gallstones 2015 G1.jpg
The gallbladder stores bile. Bile helps your body digest food. Sometimes, the parts of bile mix together. This can make stones. Some stones are made of cholesterol. Others are made of bilirubin.
Types of Gallstones.jpg
Types of Gallstones.jpg
These stones can be many colors. They might look yellow, green, or brown.

Most people with stones feel nothing at all. These are called silent stones. But sometimes, a stone can block a path. This can cause a gallbladder attack. You might feel sharp pain in your upper belly.

Gallstones.png
Gallstones.png
This pain can also move to your shoulder. A doctor can find stones using an ultrasound. This is a tool that uses sound to see inside you.

If stones cause pain, you may need help. Doctors often suggest surgery to remove the gallbladder. This is done using general anesthesia. This means you sleep during the whole thing. After the gallbladder is gone, most people feel much better.

Benefits.png
Benefits.png
You can also stay healthy with a good diet and exercise.

178 words

Gallstones are small, hard objects that form inside the gallbladder. The gallbladder is a small organ that stores bile, a fluid that helps your body digest food. When these stones form, the condition is called cholelithiasis. If a stone moves into the bile ducts, it is called choledocholithiasis.

Human gallstones 2015 G1.jpg
Human gallstones 2015 G1.jpg
Many people do not even know they have them. In fact, about 60% to 80% of people with stones have no symptoms at all. These are often called "silent stones." They can stay in the body for many years without causing any trouble.

Stones form through a specific way it works within the bile. Bile is made of things like cholesterol, bile salts, and bilirubin. If there is too much cholesterol and not enough bile salts, stones can grow.

Types of Gallstones.jpg
Types of Gallstones.jpg
Another factor is how the gallbladder moves. If it does not empty often or well, the bile can become too thick. This can cause the parts to crystallize into a solid stone. Some stones are mostly cholesterol, while others are mostly bilirubin, which are called pigment stones.
Gallstone µCT.jpg
Gallstone µCT.jpg

Doctors look for certain signs to see if stones are causing problems. A "gallbladder attack," or biliary colic, happens when a stone blocks a duct. This causes a sudden, sharp pain in the upper right part of the abdomen.

Gallstones.png
Gallstones.png
This pain often peaks about one hour after it starts. Sometimes, the pain can even be felt in the right shoulder. Other complications can happen if the stones cause inflammation. This might include cholecystitis, which is inflammation of the gallbladder, or pancreatitis, which affects the pancreas. Symptoms of these issues can include fever, vomiting, or yellowish skin.

Many different things can change a person's risk for getting stones. For example, women and people over age 40 are more likely to have them.

Prevalence2.png
Prevalence2.png
Risk can also be linked to things like obesity, diabetes, or rapid weight loss. Certain ethnic groups have different rates, too. In some places, 48% of Native Americans experience gallstones. In other parts of the world, such as Africa, the rate is as low as 3%. In developed countries, about 10% to 15% of adults have gallstones. In 2013, gallbladder-related diseases affected about 104 million people.

If stones cause pain, there are several ways to help. Doctors often use an ultrasound to see the stones inside the body.

Ultrasonography of sludge and gallstones, annotated.jpg
Ultrasonography of sludge and gallstones, annotated.jpg
If a person has many attacks, a doctor might recommend surgery to remove the gallbladder. This is usually done while the patient is under general anesthesia, which means they are asleep. In rare cases where surgery is not possible, doctors might use medicine to dissolve the stones.
Benefits.png
Benefits.png
You can also help prevent stones by eating a healthy diet and exercising to maintain a healthy weight.

466 words

Gallstones are solid objects that form inside the gallbladder, a small organ that stores bile. Bile is a fluid that helps the body digest food. When stones form within the gallbladder, the condition is called cholelithiasis. If a stone moves out of the gallbladder and into the bile ducts, it is called choledocholithiasis.

Human gallstones 2015 G1.jpg
Human gallstones 2015 G1.jpg
Many people live with these stones without knowing it. Between 60% and 80% of people with gallstones are asymptomatic, meaning they show no symptoms. These are often called "silent stones." They can remain in the body for many years without causing any medical trouble.

To understand how stones form, we must look at the chemistry of bile. Bile is composed of several substances, including cholesterol, bile salts, and bilirubin. Stones typically develop when the balance of these components changes. For example, cholesterol stones form when the bile contains too much cholesterol and not enough bile salts.

Types of Gallstones.jpg
Types of Gallstones.jpg
Another factor is how the gallbladder moves, or its motility. If the gallbladder does not contract often or effectively, the bile can become overconcentrated. This process allows the components to crystallize into solid stones. Certain proteins in the liver and bile can also encourage this crystallization process.

Scientists classify gallstones into different types based on what they are made of. Cholesterol stones are the most common type. They can vary in color from light yellow to dark green, brown, or even chalk white. These stones are usually oval and can be between 2 and 3 cm long.

Gallstone µCT.jpg
Gallstone µCT.jpg
Pigment stones are another major category. These are formed primarily from bilirubin. Pigment stones are more frequently seen in the developing world. Other stones can be "mixed," meaning they contain a combination of different materials. The specific composition of a stone is often influenced by a person's age, diet, and ethnicity.

When gallstones cause problems, the most common symptom is biliary colic. This is often called a "gallbladder attack." An attack happens when a stone blocks the cystic duct or the opening to the gallbladder. This blockage increases the pressure inside the organ as it tries to contract.

Gallstones.png
Gallstones.png
The result is a sudden, intense, cramp-like pain in the upper right abdomen. This pain usually peaks about one hour after it starts and typically subsides within five hours. Some patients also experience nausea or vomiting. In some cases, the pain is felt in the right shoulder, a phenomenon known as "Collin's sign."

If the stones are not managed, they can lead to serious medical complications. Acute cholecystitis is the inflammation of the gallbladder, often caused by stones. This pain is different from a standard attack because it lasts longer than six hours.

Ultrasonography of sludge and gallstones, annotated.jpg
Ultrasonography of sludge and gallstones, annotated.jpg
Other serious issues include pancreatitis, which is inflammation of the pancreas. This occurs if a stone slips into the pancreatic duct or the ampulla of Vater. There is also a risk of ascending cholangitis, a dangerous infection of the bile ducts. In rare cases, a very large stone can erode through the gallbladder wall and enter the small intestine, causing an obstruction known as gallstone ileus.

Many factors can increase the risk of developing gallstones. Women and people over the age of 40 are at a higher risk. Obesity, diabetes, and rapid weight loss are also known risk factors.

Prevalence2.png
Prevalence2.png
Diet plays a significant role as well. A low intake of nutrients like magnesium, calcium, and vitamin C may increase risk. Interestingly, certain foods like wine and whole-grain bread might actually decrease the risk. Ethnicity also plays a part in how common these stones are. For instance, 48% of Native Americans experience gallstones, while the rate in parts of Africa is as low as 3%.

In developed countries, between 10% and 15% of adults experience gallstones. In 2013, gallbladder and biliary-related diseases affected approximately 104 million people. This accounted for about 1.6% of the global population.

Risks.png
Risks.png
If a person experiences frequent gallbladder attacks, doctors usually recommend surgery to remove the gallbladder. This is often performed under general anesthesia using either small incisions or one larger incision.
Benefits.png
Benefits.png
In rare instances where surgery is not an option, doctors may use medication to dissolve the stones or use lithotripsy to break them down. Once the gallbladder is removed, the medical outcomes for patients are generally positive.

718 words
🖼️ Images & Media (17)
File:Human gallstones 2015 G1.jpg
Human gallstones 2015 G1.jpg
File:Types of Gallstones.jpg
Types of Gallstones.jpg
File:Gallstone µCT.jpg
Gallstone µCT.jpg
Gallenstein FRONT.OGG
File:Ultrasonography of sludge and gallstones, annotated.jpg
Ultrasonography of sludge and gallstones,...
File:Big Gallstone.JPG
Big Gallstone.JPG
File:Gallstones.png
Gallstones.png
File:StonesXray.PNG
StonesXray.PNG
File:Gallstones.JPG
Gallstones.JPG
File:Benefits.png
Benefits.png
File:LargeGstoneMark.png
LargeGstoneMark.png
File:Risks.png
Risks.png

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